TIF procedure patients experienced similar reduction in reflux symptom resolution with significantly reduced operative times compared to Nissen or Toupet fundoplication techniques
SAN MATEO, Calif. (Sept 3, 2014)–EndoGastric Solutions® (EGS), a leader in endoluminal reconstructive treatment for gastroesophageal reflux disease (GERD), announced publication of an independent study entitled Transoral Incisionless Fundoplication: Is It as Safe and Efficacious as a Nissen or Toupet Fundoplication? The study demonstrated that transoral incisionless fundoplication (TIF) provides dramatic symptom resolution, similar to that achieved after laparoscopic Nissen or Toupet fundoplication.
In each of the treatment arms, most patients experienced GERD symptoms less than once per month—after TIF procedure 83%, after Nissen 80%, and after Toupet 92%. Operative times were significantly shorter with the TIF procedures averaging 71 minutes vs 119 minutes for Toupet and 85 minutes for Nissen. In addition, length of postoperative hospital stay was significantly shorter after the TIF procedure.
“The TIF procedure is safe and effective in relieving excess gastroesophageal reflux symptoms,” said Alexander Rosemurgy, MD, Florida Hospital Tampa “In our patient series, the TIF procedure provided added benefits of shorter recovery times, and is the most minimally invasive option for symptomatic reflux patients.”
The authors concluded, “Patient satisfaction and effective palliation of symptoms prove that the TIF procedure is safe and efficacious in comparison to LESS Nissen and Toupet fundoplication surgeries, and we offer strong support for its continued application and evaluation.”
“Having new data published independently comparing our TIF procedure to the current standard of careis another important milestone for EGS, and adds to the growing body of clinical evidence surrounding our technology,” said Skip Baldino, EGS President and CEO. “It is significant for GERD patients needing a less invasive option, that the TIF procedure outcomes have been clinically validated to be similar to traditional surgery.”
The results were published in the September issue of the American Surgeon, the official journal of the Southeastern Surgical Congress and the Southern California Chapter of the American College of Surgeons. This data is from a case controlled study of three cohorts, each with 20 patients—TIF procedure, laparoscopic Nissen and Toupet fundoplication—that were controlled for age, BMI, and pH scores. Abstract is available here.